Clinicopathologic Features Of Colorectal Cancer At RSUD Dr. H. Chasan Boesoirie Ternate 2018-2023
Abstract
According to the International Agency for Research on Cancer (IARC), colorectal cancer or colon cancer includes cancer of the colon and rectum. Colorectal cancer is the 3rd most common cancer and the 4th most common cause of death related to cancer and according to GLOBOCAN in 2020 CRC is the 2nd most cases of death. The purpose of this study is to determine how the clinicopathological Features of colorectal cancer at RSUD Dr. H. Chasan Boesoirie ternate in 2018-2023, based on parameters such as age, gender, histopathology type, degree of differentiation, clinical symptoms, and cancer location. This study is an observational descriptive study with a cross-sectional approach. The sample of this study amounted to 29 samples, taken using total sampling technique. The results of the study are 29 cases where most were in the age range of 51-60 years namely 10 cases (34.5%), with 16 cases (55.2%) were males. The most clinical symptoms are bloody stools, as many as 14 cases (48.3%), and most located in the rectum, namely 15 samples (51.7%), In addition, the most common histopathological type is adenocarcinoma as many as 25 samples (86.2%) followed by the degree of tumor differentiation are well-differentiated, which was the most cases namely 22 samples (72.9%). Most cases were in the age range of 51-60 years with male gender and bloody stool as clinical symptoms, most located in the rectum with histopathology type mostly are adenocarcinoma well-differentiated.
Keyword: adenocarcinoma; colorectal cancer; clinicopathology
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Gonzales RS. Colon General WHO Classification [Internet]. Pathology Outlines. 2021 [cited 2023 Nov 15]. Available from: https://www.pathologyoutlines.com/topic/col ontumorwhoclassification.html
Vinay K, Abdul KA, Aster JC. Robbins' Basic Pathology Textbook. 10 Edition. Ham M, Saraswati M, editors. Jakarta: Elsevier; 2018. 623 p.
International Agency for Research on Cancer (IARC). IARC Handbooks Colorectal Cancer. Grants Regist 2019 [Internet]. 2019;17(November 2017):411–2. Available from: http://dx.doi.org/10.1007/978-1-349-95810-8_652
Mármol I, Sánchez-de-Diego C, Dieste AP, Cerrada E, Yoldi MJR. Colorectal carcinoma: A general overview and future perspectives in colorectal cancer. Int J Mol Sci. 2017;18(1).
Globocan. eds, Global Cancer Observatory: Cancer Today [Internet]. International Agancy for Research on Cancer. 2020 [cited 2023 Feb 12]. p. 1–2. Available from: https://gco.iarc.fr/today/home
Lotfollahzdeh S, Recio-Boiles A, Cagir B. Colon Cancer. Statpearls, Treasure Island; 2021 [cited 2023 Feb 12]. Available at : https://www.ncbi.nlm.nih.gov /books/NBK 470380/.
Amin M, Edge S, Greene F. AJCC Cancer Staging Manual. 8th ed. 2017; 8th ed. New York. Springer.
Gunasekaran V, Ekawati NP, Sumadi IWJ. Clinicopathologic Characteristics of Colorectal Carcinoma at Sanglah General Hospital, Bali, Indonesia 2013-2017. Intisari Sains Medis. 2019;10(3):552–6.
Kurniawan T, Zahari A, Asri A. Relationship between Age and Depth of Invasion and Histopathological Features in Patients with Colorectal Carcinoma in the Anatomical Pathology Section of the Faculty of Medicine, UNAND in 2008 to 2012. Andalas J Health. 2017;6(2):351.
Rubin E, Reisner MH. Essential of Rubin’s Pathology. 6th ed. North American: Lippincott William & Wilkins, Philadelphia; 2014. 387 p.
Sanjaya IWB, Lestarini A, Dwi M, Bharata Y. Clinical Characteristics of Colorectal Cancer Patients Undergoing Colonoscopy at Sanjiwani Gianyar Hospital 2019 - 2020. Aesculapius Med J. 2023;3(1):43–8.
Kim SE, Paik HY, Yoon H, Lee JE, Kim N, Sung MK. Sex- and gender-specific disparities in colorectal cancer risk. World J Gastroenterol. 2015;21(17):5167–75.
Harvey BJ, Harvey HM. Sex Differences in Colon Cancer: Genomic and Nongenomic Signalling of Oestrogen. Genes (Basel). 2023;14(12).
Devi PJC, Sriwidyani NP, Ekawati NP. Clinicopathological Characteristics of Colorectal Tumor Patients Who Underwent Colonoscopic Biopsy at Sanglah General Hospital Denpasar 2015-2017. Udayana Medical J. 2020;9:59.
Ramanathan S, Ojili V, Ravi V, Arpit N. Large Bowel Obstruction in the Emergency Department: Imaging Spectrum of Common and Uncommon Causes. J Clin Imaging Sci. 2017;7:2.
Sayuti M, Syahriza M, Ami GC. Histopathology of colorectal cancer in Cut Meutia Hospital, Aceh-Indonesia from 2017-2020. Bali Med J. 2022;11(3):1771–3.
Almuhanna R, Al-Thoubaity F, Almalki K, Algarni N, Hamad R, Makhtoum T. Clinicopathological Characteristics and Overall 5-Year Survival of Colorectal Cancer: A Retrospective Study. J Med Sci (Basel, Switzerland). 2022;10(3).
Muhajir HA, Nur IM, Yulianto FA. Characteristics of Colorectal Cancer Patients in the Anatomical Pathology Section of Al-Islam Hospital Bandung Period 2012-2016. J UNISBA. 2017;3(2):61–71.
Nagtegaal ID, Odze RD, Klimstra D, Paradis V, Rugge M, Schirmacher P, et al. Digestive System Tumours by WHO Classification of Tumours Editorial Board. 5th ed. World Health Organization, editor. World Health Organization; 2019. 141 p.
Liu Z. Gastrointestinal cancers. Diaz JAM, editor. Radiomics and Radiogenomics: Technical Basis and Clinical Applications. Australia: Exon Publication; 2022. 1–9 p.
Romus I, Nisa’ K. Clinicopathologic Profile of Colorectal Mass Biopsy in Anatomical Pathology Installation of RSUD Arifin Achmad Riau Province January 2015 - December 2019 Period. J Medical Science. 2021;15(1):32.
Fleming M, Ravula S, Tatishchev SF, Wang HL. Colorectal carcinoma: Pathologic aspects. J Gastrointest Oncol. 2012;3(3):153–73.
Tsabit SS, Trianto HF, Pratiwi SE, Hartono H. Clinicopathological Profile of Colorectal Adenocarcinoma in the Anatomical Pathology Laboratory of Dr. Soedarso Hospital Pontianak. Indones J Cancer. 2023;17(4):292.
American Cancer Society. Your Colon or Rectal Pathology Report: Invasive Adenocarcinoma. 2023;1–6. Available from: https://www.cancer.org/cancer/diagnosis-staging/tests/biopsy-and-cytology-tests/understanding-your-pathology-report/colon-pathology/invasive-adenocarcinoma-of-the-colon.html
DOI: https://doi.org/10.29103/averrous.v10i1.15653
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