Peripheral Blood Smear Eosinophil Differential Count Comparison in Patients with Skabies and After One Week Recovered from Scabies
Abstract
Scabies is a skin infection disease caused by infestation and sensitization of the mite Sarcoptes scabiei, easily transmitted from person to person. Immune response has a crucial role in secondary complications and morbidity of individuals with scabies. Eosinophil is essential in defense against parasites but also contribute to tissue dysfunction and damage in allergic diseases. The purpose of this study was to compare the peripheral blood eosinophils differential count of patients while suffering from scabies and one week after recovered from scabies. This is an analytic comparative study with a cohort design. Sample size of 30 subjects calculated with sample size formula for paired categorical-numeric analytic research. Wilcoxon test was performed for data analysis due to the data not normally distributed. The result of this study showed the mean peripheral blood differential eosinophil count of patients while suffering from scabies was 3,6% (3% - 5%) whereas one week after recovered from scabies was 2,37% (2% - 3%). There was signicant difference in the peripheral blood differential eosinophils count between patients while suffering from scabies and one week after recovered from scabies with a p value <0.05.
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World Health Organization. Scabies [internet]. (Updated 23 May 2023; cited 8 August 2023). Available from: https://www.who.int/news-room/fact-sheets/detail/scabies
Kementerian Kesehatan Republik Indonesia. Profil Kesehatan Indonesia 2018 [internet]. (Updated June 2019; cited 8 August 2023). Available from: https://www.kemkes.go.id/downloads/resources/download/pusdatin/profil-kesehatan-indonesia/profil-kesehatan-indonesia-2018.pdf
Ständer S, Ständer S. Itch in Scabies—What Do We Know?. Front. Med. 2021;8:628392. doi: 10.3389/fmed.2021.628392
Trasia R F, Sari I P. Respon imun hospes terhadap Sarcoptes scabiei. J Biomedika Kesehat. 2020; 3(4):183- 192 DOI: 10.18051
Radonjic-Hoesli, S. Brüggen, M. Feldmeyer, L. Simon, H. Simon, D. Eosinophils in skin diseases Semin Immunopathol. 2021;43:393–409 https://doi.org/10.1007/s00281-021-00868-7
Dahlan M S. Besar Sampel dan Cara Pengambilan Sampel dalam Penelitian Kedokteran dan Kesehatan. Jakarta. Salemba Medika. 2010.
Putri, Y Y. Astuti, R D I. Bharata, T. Karakteristik Tanda Kardinal Penyakit Skabies Pada Santri di Pesantren. Jurnal Integrasi Kesehatan dan Sains. 2020; 2(2): 126 – 129. DOI: https://doi.org/10.29313/jiks.v2i2.5716
Nugraha, G. Badrawi, I. Pedoman Teknik Pemeriksaan Laboratorium Klinik Untuk Mahasiswa Teknologi Laboratorium Medik. Trans Info Media Jakarta. 2018.
University Of Bristol. Which test? [internet]. (updated 18 March 2023; cited 8 August 2023). Available from: https://www.bristol.ac.uk/medical-school/media/rms/red/which_test.html
Luo, J. Chen , H. Feng , Y. Chen, Y. Lei, X. Guo, S. et al. Blood Eosinophil Endotypes across Asthma and Chronic Obstructive Pulmonary Disease (COPD). 2022. https://doi.org/10.1155/2022/9656278
Chandler, D J. Fuller, L C. A Review of Scabies: An Infestation More Than Skin Deep . Dermatology. 2019; 235:79–90. doi: 10.1159/000495290
Herwanto, N. Mappasing, H. Widiantari, S. Indranarum, T. Hidayati, A N. Sawitri, Ervianti, E. Murtiastutik, D. Martodihardjo, S. Scabies incognito Dermatology Reports ; 11(s1):8083. https://doi.org/10.4081/dr.2019.8083
Hasan, T. Krause, V L. James, C. Currie, B J. Crusted Scabies; a 2-year prospective study from the Northern Territory of Australia. PLoS Negl Trop Dis. 2020; 14(12): e0008994. https://doi.org/ 10.1371/journal.pntd.0008994
Sanchez-Flores, X. Cancel-Artau, K J. Figueroa, L. Eosinophilia with leukemoid reaction secondary to Sarcoptes scabiei JAAD Case Reports. 2021; 8:13-5. https://doi.org/10.1016/j.jdcr.2020.12.002
Nakamura K. A Case of Papuloerythroderma Secondary to Crusted Scabies. J Cutan Immunol Allergy. 2019;2:174–175.
DOI: https://doi.org/10.29103/averrous.v9i2.12416
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