The Possible Role of Plant Derived Essential Oils Against Fatigue in Post Acute Sequele Covid-19: A Literature Review Based on Evidence of Essential Oils on Fatigue
Abstract
Symptoms of COVID-19 were found to be persistent after acute onset in some survivors. One of the Post Acute Sequele Covid-19 (PASC) problems is fatigue. Until now, the treatment options for fatigue in PASC are limited. Plant derived essential oils (EO) have been shown to reduce fatigue in several patient populations. The aim of this review is to present all the evidence regarding the benefits of plant derived EO for fatigue, whether they can be used as a therapy for fatigue associated PASC. Method: Literature search was conducted on the PubMed, Science Direct, Google Schoolar, and Springer Link databases focusing on the last 10 years randomized clinical trial (RCT) study on the topic of the effect of EO on fatigue with the keywords ‘Essential Oils’, ‘Fatigue’ and ‘Long Covid-19’. The evidence and other information obtained is then analyzed using PICO synthesis and presented in tabular and narrative form. Results: Based on the analysis of the 11 articles obtained, it was found that the utilization of plants EO such as Lavender, Sweet Orange; Lavender mixed Cananga, Juniper, and Rosemary; Sandalwood mixed Frankincense and Ravensara; Evening Primrose; leaves of Peppermint mixed Black Pepper, Clove Bud, White Grapefruit and Bergamot have been shown to reduce fatigue in several patient populations compared to control group. Conclusion: Plant derived EO may have a role and be useful for reducing fatigue in PASC.
Keywords
Full Text:
PDFReferences
Aiyegbusi OL, Hughes SE, Turner G, Rivera SC, McMullan C, Chandan JS, et al. (2021) “Symptoms, complications and management of long COVID: a review.” Journal of the Royal Society of Medicine 114: 428–42.
Greenhalgh T, Knight M, A’Court C, Buxton M, Husain L. (2020) “Management of post-acute covid-19 in primary care.” The BMJ: 370.
Estiri H, Strasser ZH, Brat GA, Semenov YR, Consortium T, Ehr C-, et al. (2021) “Evolving phenotypes of non-hospitalized patients that indicate long COVID.” BMC Medicine:1–10.
Carfì A, Bernabei R, Landi F. (2020) “Persistent symptoms in patients after acute COVID-19.” Journal of the American Medical Association 324: 603–5.
Huang C, Huang L, Wang Y, Li X, Ren L, Gu X, et al. (2021) “6-month consequences of COVID-19 in patients discharged from hospital: a cohort study.” The Lancet 397(10270): 220–32.
Susanto. (2021) “Clinical picture and quality of life of post-COVID-19 patients in Indonesia.” In: the 18th Scientific Respiratory Medicine Meeting. Department of Pulmonology, Faculty of Medicine, University of Indonesia - Persahabatan Hospital.
Shah W, Hillman T, Playford ED, Hishmeh L. (2021) “Managing the long term effects of covid-19: Summary of NICE, SIGN, and RCGP rapid guideline.” The BMJ: 372.
Mantovani E, Mariotto S, Gabbiani D, Dorelli G, Bozzetti S, Federico A, et al. (2021) “Chronic fatigue syndrome: an emerging sequela in COVID-19 survivors?.” Journal of NeuroVirology 27(4): 631–7.
Toogood PL, Clauw DJ, Phadke S, Hoffman D. (2021) “Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Where will the drugs come from?.” Pharmacological Research 165: 1-10.
Mackay A. (2021) “A Paradigm for Post-Covid-19 Fatigue Syndrome Analogous to ME/CFS. Frontiers in Neurology 12: 1-10.
Shirzadegan R, Gholami M, Hasanvand S, Beiranvand A. (2020) “The effects of Citrus aurantium aroma on anxiety and fatigue in patients with acute myocardial infarction: A two-center, randomized, controlled trial.” Journal of Herbal Medicine 21: 1-8.
Hassanzadeh M, Farsi Z, Sajadi SA. (2021) “Comparison of the effect of Sedamin and aromatherapy with Lavender on fatigue severity of patients with heart failure: A three arm randomized controlled trial.” Journal of Herbal Medicine 30: 1-6.
Choi SY, Park K. (2016) “Effect of Inhalation of Aromatherapy Oil on Patients with Perennial Allergic Rhinitis: A Randomized Controlled Trial.” Evidence-based Complementary and Alternative Medicine 2016: 1-7.
Hawkins J, Hires CY, Dunne EW, Keenan LA. (2020) “Aromatherapy reduces fatigue among women with hypothyroidism: A randomized placebo-controlled clinical trial.” Journal of Complementary and Integrative Medicine 17(1): 1-9.
Ahmady S, Rezaei M, Khatony A. (2019) “Comparing effects of aromatherapy with lavender essential oil and orange essential oil on fatigue of hemodialysis patients: A randomized trial.” Complementary Therapies in Clinical Practice 36: 64–8.
Varaei S, Jalalian Z, Yekani Nejad MS, Shamsizadeh M. (2021) “Comparison the effects of inhalation and massage aromatherapy with lavender and sweet orange on fatigue in hemodialysis patients: A randomized clinical trial.” Journal of Complementary and Integrative Medicine 18(1): 193–200.
Majdinasab N, Namjoyan F, Taghizadeh M, Saki H. (2018) “The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis.” Neuropsychiatric Disease and Treatment 14: 1505–12.
Gok Metin Z, Ozdemir L. (2016) “The Effects of Aromatherapy Massage and Reflexology on Pain and Fatigue in Patients with Rheumatoid Arthritis: A Randomized Controlled Trial.” Pain Management Nursing 17(2):140–9.
Asif M, Saleem M, Saadullah M, Yaseen HS, al Zarzour R. (2020) “COVID-19 and therapy with essential oils having antiviral, anti-inflammatory, and immunomodulatory properties.” Inflammopharmacology 28: 1153–61.
Islam MF, Cotler J, Jason LA. (2020) “Post-viral fatigue and COVID-19: lessons from past epidemics.” Fatigue: Biomedicine, Health and Behavior 8(2): 61–9.
Proal AD, VanElzakker MB. (2021) “Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms.” Frontiers in Microbiology 12: 1-24.
Vollbracht C, Kraft K. (2021) “Feasibility of vitamin c in the treatment of post viral fatigue with focus on long covid, based on a systematic review of iv vitamin c on fatigue.” Nutrients 13(4): 1-11.
Kamalabadi M, Astani A, Nemati F. (2018) “Anti-viral Effect and Mechanism of Carvacrol on Herpes Simplex Virus Type 1.” International Journal of Medical Laboratory 5: 1-10.
Muz G, Taşcı S.(2017) “Effect of aromatherapy via inhalation on the sleep quality and fatigue level in people undergoing hemodialysis.” Applied Nursing Research 37: 28–35.
Hassanzadeh M, Kiani F, Bouya S, Zarei M. (2018) “Comparing the effects of relaxation technique and inhalation aromatherapy on fatigue in patients undergoing hemodialysis.” Complementary Therapies in Clinical Practice 31: 210–4.
Karadag E, Samancioglu Baglama S. (2019) “The Effect of Aromatherapy on Fatigue and Anxiety in Patients Undergoing Hemodialysis Treatment: A Randomized Controlled Study.” Holistic Nursing Practice 33(4): 222–9.
Timoszuk M, Bielawska K, Skrzydlewska E. (2018) “Evening primrose (Oenothera biennis) biological activity dependent on chemical composition.” Antioxidants 7: 1-11.
Dev Sharma A, Kaur I. Jensenone from eucalyptus essential oil as a potential inhibitor of COVID 19 corona virus infection. Available from: https://creativecommons.org/licenses/by/4.0/
DOI: https://doi.org/10.29103/averrous.v9i2.11563
Article Metrics
Abstract Views : 229 times
PDF Downloaded : 6 times
Refbacks
- There are currently no refbacks.
Copyright (c) 2023 Fauzi Satria
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
| Print ISSN | : |
2477-5231 |
| Online ISSN |
: |
2502-8715 |
Publisher:
Fakultas Kedokteran Universitas Malikussaleh
Kampus Fakultas Kedokteran Universitas Malikussaleh, Jl. Meunasah, Uteunkot Cunda, Lhokseumawe, 24351, Provinsi Aceh, Tel/fax : 081376575984, Email: averrous@unimal.ac.id
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.