PERANAN PROTEIN ADHESI MATRIKS EKSTRASELULAR DALAM PATOGENITAS BAKTERI STAPHYLOCOCCUS AUREUS
Abstract
Bakteri Staphylococcus merupakan salah satu bakteri yang sering menimbulkan infeksi pada manusia.Beberapa spesiesnya merupakan flora normal pada kulit dan selaput lendir manusia, ada yang bersifat patogen yang dapat menyebabkan infeksi piogenik bahkan septikemia. Staphylococcus aureus merupakan spesies yang paling invasif. Bakteri ini memiliki beragam faktor virulensi, yang mencakup protein-protein permukaan yang berperan dalam perlekatan kuman, enzim-enzim yang menguraikan protein, dan toksin yang merusak sel penjamu. Faktor virulensi S. aureus saling mempengaruhi, dengan struktur dan sekresi produknya yang berperan dalam patogenesis infeksi. Banyak faktor yang berperan dalam patogenitas bakteri Staphylococcus aureus, mulai dari metabolit bakteri, faktor virulensi sampai perananprotein adhesi matriks ekstraseluler.
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DOI: https://doi.org/10.29103/averrous.v4i2.1041
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